101 Best Missouri Information Technology Companies and Startups

August 9, 2021
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This article showcases our top picks for the best Missouri based Information Technology companies. These startups and companies are taking a variety of approaches to innovating the Information Technology industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

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Top Missouri Information Technology Startups

Data sourced from Crunchbase and SemRush.

Adalo

Adalo

Crunchbase Website Twitter Facebook Linkedin

Adalo is a computer software company that specializes in the fields of Android, software, and information technology.

Daupler

Daupler

Crunchbase Website Twitter Facebook Linkedin

Daupler simplifies the way people communicate with local government and utilities.

Daupler

Lumeris

Crunchbase Website Twitter Facebook Linkedin

Lumeris is an accountable care delivery innovation company

Daupler

TierPoint

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TierPoint has rapidly become the premier carrier-class and carrier-neutral Data Center services provider in the Inland Northwest.

Daupler

Essence Group Holdings

Crunchbase Website Twitter Facebook Linkedin

Essence Group Holdings offers health insurance and software solutions necessary for health systems, health plans and provider organizations.

Daupler

Engagedly

Crunchbase Website Twitter Facebook Linkedin

Enterpise HR Tech SaaS platform for Engagement driven Performance Management, Learning and Rewards

Daupler

DisruptOps

Crunchbase Website Twitter Facebook Linkedin

DisruptOps is a cloud security operations platform that helps customers find & fix security issues before they become incidents.

Daupler

Neocova

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Neocova is a financial services company that specializes in providing artificial intelligence, analytics, and other cloud-based systems.

Daupler

Transactly

Crunchbase Website Twitter Facebook Linkedin

Transactly is a real estate technology platform that organizes and coordinates the process of closing a real estate transaction.

Daupler

Pepper

Crunchbase Website Twitter Facebook Linkedin

Pepper offers an operating system and service delivery platform to empower enterprises to deploy sophisticated IoT marketplace solutions.

Daupler

Ryvit

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Ryvit develops an integration software that delivers seamless flow of data between premise and software used in the construction industry.

Daupler

Avatara

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Avatara is an MSP focused on outsourced IT, private cloud-based infrastructure and application solutions

Daupler

Exegy

Crunchbase Website Twitter Facebook Linkedin

Exegy provides ultra-high performance, hardware-accelerated computing appliances that process market data for financial organizations.

Daupler

High School Esports League

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High School Esports League is an esports league organizer. It organizes esports tournaments for high school students.

Daupler

Pathfinder Health Innovations

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Pathfinder Health Innovations is a comprehensive web-based software tool for supporting the implementation of ABA therapy.

Daupler

homewav

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Homewav is the leader in providing reliable revenue to detention facilities with comprehensive inmate video visitation solutions & hardware.

Daupler

Banks Best Rates

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Tech Financial Organization

Daupler

Isto Technologies

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ISTO Technologies is an orthobiologics firm developing biologic products to regenerate and restore function to damaged cartilage and bone.

Daupler

HomeRoom

Crunchbase Website Twitter Facebook Linkedin

HomeRoom is a co-living marketplace.

Daupler

Automotive Innovations

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Automotive Innovations builds software in the automotive industry that gives dealers actionable intelligent information.

Daupler

Applied Particle Technology

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Ensuring healthy workers in the toughest environments through automated environmental health and safety solutions

Daupler

Sparo Labs

Crunchbase Website Twitter Facebook Linkedin

Sparo Labs is an award-winning startup company in St. Louis dedicated to breathing life into the asthma industry.

Daupler

Rebate Bus, Inc.

Crunchbase Website Twitter Facebook Linkedin

Rebate Bus provides software and support to business customers promoting the sale and implementation of energy-efficient products.

Daupler

Radialogica

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Radialogica is a bioinformatics company providing software solutions for radiation oncology and the healthcare market.

Daupler

PopBookings

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PopBookings is a cloud-based software that automates the hiring process for temporary and promotional staffing companies.

Daupler

PlanIT Impact

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PlanIT Impact is a cloud-based web application that allows architects, designers, engineers, developers.

Daupler

Invisible Girlfriend

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Invisible Girlfriend, and its partner service Invisible Boyfriend, helps users tell a story about a relationship they aren’t actually in.

Daupler

Recursive Labs

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We improve customer sales & service experiences (CX) with a fully integrated, visual customer engagement platform for web, mobile & IoT

Daupler

FloEnvy

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FloEnvy is the premier software for cannabis cultivation

Daupler

iCasting

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iCasting is an online platform that brings clients and talents together.

Daupler

Oakwood

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Oakwood’s expertise in established and emerging technologies provides a unique value-add to organizations of all sizes.

Daupler

TrackMy Solutions

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TrackMy Solutions is a software and mobile application company that provides a solution for people with medical implants.

Daupler

Cloud Commerce

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Cloud Products and Services for SMBs.

Daupler

iOR Partners

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iOR Partners transforms ophthalmology practice with an office-based surgery suite.

Daupler

MedSocket

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MedSocket provides a clinical decision support system with a patented 1-Click Decision Support system and a patented medical search engine.

Daupler

MOgene

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MOgene is a provider of genomics services for academic, government, and industrial research groups and institutions.

Daupler

Helper Helper

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Helper Helper is the simplest way to track student volunteer hours.

Daupler

Brightergy

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Brightergy is a new kind of energy company that empowers organizations to take control over their energy – creation, cost, and consumption.

Daupler

9Line Software

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9Line Software delivers detailed location information with every 911 call to the correct PSAP.

Daupler

Rozzy Learning Company

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Rozzy Learning Company creates STEAM programs for Homeschoolers & PreK-3rd Graders.

Daupler

Brazen Global

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Brazen’s technology-enabled membership platform offers customized resources and a global support.

Daupler

Contegix

Crunchbase Website Twitter Facebook Linkedin

As an MSP Contegix specializes in CMS like Drupal and WordPress, the Atlassian toolset, DevOps tools, service desk and IT admin.

Daupler

Blossom

Crunchbase Website Twitter Facebook Linkedin

Blossom is a software company that connects all types of exchanges on the same marketplace.

Daupler

GIVVER

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GIVVER provides a solution that enables users to tweet a donation to their organizations and causes.

Daupler

Evogen

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Evogen provides air sampling solutions and its technology is used for military, government, and civilian environments.

Daupler

TradeHarbor

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TradeHarbor, Inc., a Delaware corporation, was founded in May, 1999 and is headquartered in St.

Daupler

Abstrakt Marketing Group

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Abstrakt Marketing Group is a marketing and consulting company providing outsourcing and virtual marketing management solutions.

Daupler

Cloud Inventory

Crunchbase Website Twitter Facebook Linkedin

Cloud Inventory® Solutions and Mobile-First Supply Chain Apps for the Digital Economy

Daupler

BenMedica

Crunchbase Website Twitter Facebook Linkedin

BenMedica helps insurers overcome the electronic channel to drive value at the point of care.

Daupler

Ripeta

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Ripeta is a software and services company assessing scientific reproducibility.

Daupler

Trizetto provider solutions

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TriZetto Provider Solutions is one of the nation’s largest healthcare electronic data interchange provider.

Daupler

T-REX

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T‐REX is a world class venue providing the startup entrepreneur with low cost & flexible enterprise space.

Daupler

Edge Up Sports

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The cleanest user experience with the richest computational data set for NFL football

Daupler

Valorem Reply

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Valorem Reply is a information technology consulting firm.

Daupler

Keystone Technologies

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Keystone Technologies is a provider of an online community network for retirement communities.

Daupler

Connectria Hosting

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Connectria is a provider of cloud computing, managed hosting, and custom hosting solutions.

Daupler

Eye Care Leaders

Crunchbase Website Twitter Facebook Linkedin

Eye Care Leaders is a Healthcare IT company providing holistic solutions to the Optometry and Ophthalmologic specialties.

Daupler

Fishtech Labs

Crunchbase Website Twitter Facebook Linkedin

Fishtech Labs is a technology accelerator focused on finding

Daupler

Sherpa CRM

Crunchbase Website Twitter Facebook Linkedin

Sherpa’s interactive CRM sales solution for the senior living industry revolutionizes sales management.

Daupler

Edis Solutions

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Edis Solutions is developing a platform that uses pharmaceutical drug data and dissects it into an easy-to-use platform.

Daupler

Electric Power Systems

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Electric Power Systems is a utilities company that provides commissioning and maintenance testing services.

Daupler

Just.Cash

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Just Cash provides customers with easy access to cash using their own mobile devices.

Daupler

NameHero

Crunchbase Website Twitter Facebook Linkedin

NameHero is a high speed cloud web hosting provider and domain management platform for consumers and small businesses.

Daupler

Rose International

Crunchbase Website Twitter Facebook Linkedin

Rose International is provider of Workforce Solutions and Information Technology Solutions .

Daupler

Battenfeld Technologies

Crunchbase Website Twitter Facebook Linkedin

Battenfeld Technologies Inc. is a manufacturer of shooting, reloading, gunsmithing and gun cleaning supplies. Battenfeld manufactures

Daupler

KNOW iNK

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KNOW iNK is a designer and provider of election and polling place software.

Daupler

RedCard

Crunchbase Website Twitter Facebook Linkedin

RedCard is an information technology company providing data management and BPO services

Daupler

IonWave Technologies

Crunchbase Website Twitter Facebook Linkedin

Ion Wave Technology’s software applications .

Daupler

Pushly

Crunchbase Website Twitter Facebook Linkedin

Pushly is a platform designed to enhance audience engagement through push notifications.

Daupler

Partek Inc.

Crunchbase Website Twitter Facebook Linkedin

Partek is a software company that provides easy-to-use genomic data analysis solutions for scientists.

Daupler

Aggio

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Aggio is an information technology company that provides a cloud-based platform for marketing solutions on agriculture industry.

Daupler

Conference Technologies

Crunchbase Website Twitter Facebook Linkedin

A complete solutions provider for audio visual, video, and information technology integration

Daupler

Unidev

Crunchbase Website Twitter Facebook Linkedin

Enterprise Development, Custom Software Development, Web Development, Digital Marketing, and Web & Software Support Services

Daupler

InterCard

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InterCard AG, a leading Payment as a Service provider in Germany

Daupler

CenturyLink Technology Solutions

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Savvis provides cloud and managed solutions for enterprises and government clients worldwide.

Daupler

ClubReady

Crunchbase Website Twitter Facebook Linkedin

Fast-growing provider of easy-to-use business management software for the fitness and wellness industry

Daupler

Juxly

Crunchbase Website Twitter Facebook Linkedin

Juxly is a pioneering platform that offers an efficient app that enables healthcare professionals to improve patient care and earnings.

Daupler

Daugherty Business Solutions

Crunchbase Website Twitter Facebook Linkedin

Daugherty Business Solutions is an Information Technology and Services providing company.

Daupler

Equity.com

Crunchbase Website Twitter Facebook Linkedin

Equity.com is a new type of technology investment fund.

Daupler

Barry-Wehmiller

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Barry-Wehmiller is a company that provides manufactures packaging and paper processing equipment.

Daupler

Trans States Airlines

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Trans States Airlines is an flights providing service company.

Daupler

Hub Enterprises, Inc

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Hub Enterprises is a security and investigations company providing surveillance, activity checks, and claim investigations services.

Daupler

Final Thoughts

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Final Thoughts connects loved ones during and after life.

Daupler

WorkOtter

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WorkOtter is a simpler, lower cost, and adaptive Cloud suite that makes capacity planning and project delivery a snap.

Daupler

ADB Companies

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ADB Companies is a utilities company specializing in wireless and zero-day technology solutions.

Daupler

Safe Haven Security Services, Inc.

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Safe Haven Security Services is a security and investigations company that provides burglar protection and smoke detection services.

Daupler

Equus Compute Solutions

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Equus Compute Solutions is a computer hardware company offering custom and stock solutions.

Daupler

CSI Leasing

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CSI Leasing is a technology leasing company that offers solutions that help maximize budget dollars and increase efficiency

Daupler

evolve24

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evolve24 is a data analytics and insights company that measures audience perception to help marketers in business decision making process.

Daupler

Ivani

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Ivani offers a platform human presence detection technology called Network Presence Sensing.

Daupler

Symvato

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Symvato provides self-paced HIPAA compliance tools for healthcare providers.

Daupler

Dynamic Consultants Group

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Dynamic Consultants Group provides business intelligence, business process management, and field services.

Daupler

Client Services Incorporated

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Client Services Incorporated is a financial services company that provides customer relationship management services.

Daupler

Transaction Data Systems

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Transaction Data Systems is in pharmacy software solutions for the community pharmacy market.

Daupler

XIL Health

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XIL Health creates strategies and innovative technologies that help stabilize the business and diversify revenue streams.

Daupler

Artisan Technology Group

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Artisan Technology Group delivers transformative technology solutions and digital experiences that solve complex business challenges.

Daupler

Bradford & Galt

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Bradford & Galt is an information technology company that offers IT services and talent solutions.

Daupler

Sellozo

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Sellozo specializes in providing PPC automation tools, advertising tools, campaign management and optimization services.

Daupler

FLS Connect

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FLS Connect is a telecommunications company that offers data management services.

Daupler

Tetrasoft

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Tetrasoft is a Global Digital Services company, focused on delivering innovation and digital services to leading companies.

Daupler

Webasto Thermo & Comfort North America, Inc.

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Webasto Thermo & Comfort North America is a transportation company providing transportation idle reduction technology services.

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