101 Top Indiana Biotechnology Companies and Startups of 2021

June 30, 2021
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This article showcases our top picks for the best Indiana based Biotechnology companies. These startups and companies are taking a variety of approaches to innovating the Biotechnology industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

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Top Indiana Biotechnology Startups

Data sourced from Crunchbase and SemRush.

Eli Lilly

Eli Lilly

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Eli Lilly engages in the discovery, development, manufacture, and sale of products in pharmaceutical products business segment.

NICO

NICO

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NICO develops medical devices for minimally invasive neurosurgery, as well as skull base and spinal surgical procedures.

NICO

OrthoPediatrics

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OrthoPediactrics designs, develops, manufactures, and distributes orthopedic implants and instruments for pediatric orthopedic surgeons.

NICO

MBX Biosciences

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MBX Biosciences is a preclinical-stage biotech company that creates therapies to treat rare endocrine diseases.

NICO

Scioto Biosciences

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Scioto is a developer of Activated Bacterial Therapeutics (ABT) platform intended to deliver live bacteria to the gut.

NICO

Outpost Medicine

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Outpost Medicine is a biopharmaceutical company

NICO

AgeneBio

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AgeneBio is a neuroscience pharmaceutical company developing treatments for diseases that impact memory.

NICO

Apexian Pharmaceuticals

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Apex Therapeutics develops and commercializes pharmaceuticals for the treatment of cancer and ocular diseases.

NICO

Fast Biomedical

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Fast Biomedical is a private, Indiana-based, clinical stage medical technology company focusing on development and commercialization.

NICO

Wellfount

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Wellfount is a pharmacy offering tech-enabled dispensing to deliver pharmacy services at the point of patient care inside a facility.

NICO

Novilytic

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Novilytic is a biochemistry analytics company that protects and secures lifesaving drugs and medical devices.

NICO

Neurodon

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Neurodon is a biopharmaceutical company focusing on developing new medicines to improve memory and cognition in Alzheimer’s Disease.

NICO

Amplified Sciences

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Amplified Sciences is a life science diagnostics company focused on accurately detecting and pre-empting the risks of debilitating diseases.

NICO

SonarMed

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SonarMed develops technology to improve the placement and monitoring of endotracheal tubes used in patients who cannot breathe on their own.

NICO

Wave Therapeutics

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Bussert Medical is a Biotechnology and Software Company focused on solving the $10B Pressure Injury problem for the mobility impaired.

NICO

Animated Dynamics

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Animated Dynamics (AniDyn) Inc. is located in the Kurz Purdue Technology Center in West Lafayette IN.

NICO

Elanco

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Elanco develops, manufactures and markets products for companion and food animals.

NICO

Activate Healthcare

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Activate Healthcare delivers proactive, preventive primary care at or near an employer’s location.

NICO

Nanovis

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Nanovis is a technology-driven growth company that develops cervical and lumbar interbody fusion devices.

NICO

Algaeon

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Algaeon supplies high-value products derived from algae to companies in the human nutraceutical and fish feed industries.

NICO

AIT Bioscience

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AIT Bioscience offers bioanalytical contract research services for preclinical and clinical trials.

NICO

Adipo Therapeutic

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Adipo Therapeutic is a biotechnology company that develops polymer-based nanotherapeutics.

NICO

Calibrium

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Calibrium is an emerging privately held biopharmaceutical company.

NICO

GoPath Laboratories LLC

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GoPath is a fully equipped, CAP Accredited and CLIA Certified Anatomic Pathology, Clinical Pathology and Molecular Diagnostic laboratory

NICO

Sexton Biotechnologies

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Sexton Biotechnologies is a biotechnology company.

NICO

Akanocure Pharmaceuticals

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Akanocure Pharmaceuticals develop biotargeted anti-cancer chemotherapeutic drugs derived from natural sources.

NICO

Sword Diagnostics

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Sword Diagnostics is a life sciences company addressing the needs of the research, pharmaceutical, and clinical communities.

NICO

Confluence Pharmaceuticals

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Confluence Pharmaceuticals is developing novel therapeutic medications for neurological development disorders

NICO

KinaRx

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KinaRx is a biotech firm focuses on the development of novel kinase inhibitors for the treatment of Acute myeloid leukemia.

NICO

BioPoly

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BioPoly is engaged in the development of orthopedic devices for the sports medicine, orthopedics, and spinal markets.

NICO

Strand Diagnostics

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Strand Diagnostics develops and markets the know error® system which utilizes bar coding and DNA testing to confirm surgical biopsy samples.

NICO

Bio-Marine Ingredients Ireland

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Bio-Marine Ingredients Ireland is a s bio-tech company.

NICO

Prosolia

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Analytical Chemistry Tool Design

NICO

IV Diagnostics

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IV Diagnostics develops diagnostic tools for detecting, measuring and monitoring rare circulating tumor cells.

NICO

Owl Manor Veterinary

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Owl Manor Veterinary is a privately held medical device company

NICO

Anagin

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Anagin is developing first-in-class therapies for treating neuropsychiatric diseases.

NICO

MaREI

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MaREI is a marine and energy-based research, development and innovation hub

NICO

ImmuneWorks

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ImmuneWorks develops immune tolerance treatments for patients with serious autoimmune diseases in the lung.

NICO

PolyGroup

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Poly Group is a patented antimicrobial technology company that develops a biocompatible antimicrobial co-polymer.

NICO

Morris Innovative

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Morris Innovative is a company that produces a vascular closure devices for medical use.

NICO

Quantum OPS

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Quantum OPS an orthopedic tech company, develops products enabling clinicians to immobilize, stabilize, and position patients for surgery.

NICO

Biologics Modular

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Biologics Modular manufactures pre-constructed and pre-tested modular cleanrooms and laboratory facilities.

NICO

Perez Forensic Strategies

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Perez Forensic Strategies (PFS) is the only Hispanic owned DNA consulting company in the United States.

NICO

NutraMaize

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NutraMaize is an Indiana based AgBioScience company commercializing a more nutritious, better tasting

NICO

Positron

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Positron is a research and development company providing full nuclear cardiology solutions.

NICO

Assembly Biosciences

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Assembly Biosciences, Inc. is a public biotechnology company and provider of oral biologic therapeutics.

NICO

Karyosoft

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Karyosoft is a Developer of a Web-based enterprise platform

NICO

GI Track

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GI Track provides data collection, analysis, and reporting tools for the management of chronic digestive diseases.

NICO

Tooth Bank

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Tooth Bank, LLC operates in the health care industry. The company was incorporated in 2014 and is based in Brownsburg, Indiana.

NICO

AGI Biopharmaceuticals

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AGI Biopharmaceuticals offers a patented melanoma vaccine with future multi-cancer applications.

NICO

INCOG BioPharma

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INCOG BioPharma services include injectable drug product formulation, analytical method, process scale up, and formulation.

NICO

Endocyte

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Endocyte is a biopharmaceutical company that develops receptor-targeted therapeutics to treat cancer and inflammatory diseases.

NICO

Cook Group

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Cook Group is a developer of health care devices offering medical research and product development.

NICO

Dow AgroSciences

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Dow AgroSciences is increasing crop productivity through higher yields, better varieties, and more targeted pest management control.

NICO

BioAnalytical Systems

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Bioanalytical Systems provides contract development services and equipment to pharmaceutical, medical research, and biotechnology companies.

NICO

Exelead

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Exelead is a dynamic platform that is expertise in developing and production of liposomal and LNP drug product formulations.

NICO

Genezen Laboratories

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Genezen Laboratories is a cell and gene therapy contract development and manufacturing organization.

NICO

Cook Pharmica, LLC

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Cook Pharmica is a privately held contract development and manufacturing organization.

NICO

Cook Biotech

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Cook Biotech is a medical device company that offers biologic tissue grafts.

NICO

Beckman Coulter Life Sciences

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Beckman Coulter Life Sciences develops, manufactures and markets products that simplify, automate and innovate complex biomedical tests.

NICO

AgReliant Genetics

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AgReliant Genetics is a leader in seed research, production and quality focused on providing trusted seed solutions that help farmers gro.

NICO

Zionexa

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Zionexa is an international and innovative company developing and commercializing in-vivo biomarkers.

NICO

Marcadia Biotech

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Marcadia Biotech is focused on developing therapeutic products to improve the daily life of people with diabetes and obesity.

NICO

Mycogen

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Mycogen Seeds is one of the few companies with global breeding capabilities and access to a world-class trait development program.

NICO

Biostorage Technologies

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BioStorage Technologies is the premier, global provider of comprehensive sample management solutions for the bioscience industry.

NICO

Zevacor

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Zevacor develops, manufactures, and distributes PET and SPECT radiopharmaceuticals.

NICO

Indiana Health Information Exchange

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Indiana Health Information Exchange is a health care service provider.

NICO

Nachi America Inc.

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Nachi America Inc. is a company that develops technology for products and processes.

NICO

Semafore Pharmaceuticals

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Semafore Pharmaceuticals discovers and develops clinical-stage drugs.

NICO

Xylogenics

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Redefining fermentation through synthetic biology

NICO

Terpenoid Therapeutics

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Terpenoid Therapeutics is a drug discovery and development company focused on drug candidates for cancer.

NICO

Polymer Technology Systems, Inc

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Polymer Technology Systems is a medical device company specializing in diagnostics solutions.

NICO

Channel Bio

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A seed company, specializes in corn, soybeans, sorghum, and alfalfa.

NICO

IKOTECH

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IKOTECH is a biotech developer of novel high-speed magnetic cell sorting systems for use in life science applications.

NICO

Indiana Hemophilia and Thrombosis Center

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Indiana Hemophilia and Thrombosis Center focuses on blood disorder research and clinical treatment.

NICO

Matrix-Bio

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MatrixBio develops metabolite-profiling technology for disease diagnosis, drug therapy analysis, and drug development.

NICO

EPP

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EPP is a GLP Contract Research Laboratory providing specialist analytical and development services in chemical and environmental science.

NICO

Agdia Inc

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Agdia is a biotechnology company that provides test kits for plant pathogens and transgenic.

NICO

Bangs Laboratories

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Bangs Laboratories manufactures polymer, silica and magnetic microsphere products for diagnostic, research and flow cytometry application.

NICO

JMI Laboratories

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JMI Laboratories is a research company specializing in antimicrobial resistance research services.

NICO

E&O Laboratories

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E&O Laboratories have been harvesting donor animal blood since 1978 on their two dedicated farm units.

NICO

Experior Healthcare Systems

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Experior Healthcare Systems is a leading developer and integrator of healthcare enterprise systems.

NICO

NERx Biosciences

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NĒRx BioSciences is a company dedicated to the discovery and development of targeted therapeutics for cancer.

NICO

Tymora Analytical Operations

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Tymora Analytical Operations provides diagnostic development and exosome proteomics contract services.

NICO

B2S Life Sciences

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B2S Life Sciences provides bioanalytical consulting, immunoassay development, and life-cycle management services.

NICO

Biodyne USA

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Biodyne USA is an environmental biotechnology company.

NICO

Structured Immunity

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Structured Immunity is a protein engineering company determined to improve the safety of T cell based therapies.

NICO

Ash Access Technology

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Ash Access Technology develops technologies and devices to treat and prevent the clinical consequences of vascular access-related diseases.

NICO

Biomineral Systems

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Biomineral Systems specializes in environmental biochemical research, technology, and consulting services.

NICO

Emerald Neuro-Recover Centers

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Emerald Neuro-Recover Centers specializes in Alcohol and Drug Addiction Treatment using NAD+ Brain Restoration Therapy.

NICO

FlowCo

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FlowCo is a medical device company developing products to improve the flow of blood through the vascular system.

NICO

EndGenitor Technologies

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Founded in 2005, EGT combined the pioneering science of Dr. Merv Yoder and Dr. David Ingram with the extensive corporate and drug

NICO

Schwartz Biomedical

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Schwartz Biomedical provides technology solutions that are designed to address tissue engineering problems.

NICO

Creative Laboratory Products

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Creative Laboratory Products producer of human and animal cholesterol concentrates.

NICO

Horizon Oncology Center

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Horizon Oncology offers a wide range of comprehensive cancer services to patients, including advanced technological options.

NICO

VitaCyte

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VitaCyte manufactures purified and characterized tissue dissociation enzymes.

NICO

Rimedion, Inc.

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Our passion, in all we do, is to improve the quality of individual health care through the development of gene therapy technologies.

NICO

Dormir

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Dormir is a biotechnology company that provides patient care for sleep disorders.

NICO

Chematics

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Chematics is a privately held biotechnology company.

NICO

Medivative Technologies

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Medivative Technologies is a medical devices company offering the medical device.

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