101 Top Minnesota Medical Companies and Startups of 2021

July 5, 2021
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This article showcases our top picks for the best Minnesota based Medical companies. These startups and companies are taking a variety of approaches to innovating the Medical industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

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Top Minnesota Medical Startups

Data sourced from Crunchbase and SemRush.

Medtronic

Medtronic

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Medtronic develops and manufactures medical device technologies and therapies to treat chronic diseases worldwide.

Mayo Clinic

Mayo Clinic

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MayoClinic is a nonprofit medical practice and medical research group focused on integrated health care, education, and research.

Mayo Clinic

Miromatrix Medical

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Miromatrix Medical is engaged in the development of fully biological human organs and organ-derived biological products.

Mayo Clinic

CVRx

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CVRx is a medical device company developing implantable technology for the treatment of high blood pressure.

Mayo Clinic

Inspire Medical Systems

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Inspire Medical Systems develops implantable therapeutic devices for the treatment of obstructive sleep apnea.

Mayo Clinic

Predictive Oncology

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Predictive Oncology is working with the pharmaceutical, diagnostic, and biotech industries to develop customizable assessment methods.

Mayo Clinic

ABILITY Network

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ABILITY Network offers CMS-approved, secure Medicare and all-payer online access for claims processing and reimbursement.

Mayo Clinic

Zipnosis

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Zipnosis is a hospital and healthcare company that specializes in online diagnosis and triage, telehealth, and virtual care.

Mayo Clinic

HistoSonics

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HistoSonics specializes in developing medical devices, interventional radiology, and surgical robotics.

Mayo Clinic

Vireo Health

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Vireo Health is a physician-led company dedicated to providing patients with best-in-class cannabis-based products and high quality care

Mayo Clinic

Monteris Medical

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Monteris Medical is a medical device venture that develops new technologies for the treatment of cancer.

Mayo Clinic

MIVI Neuroscience

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MIVI Neuroscience focuses on developing and commercializing clinical solutions for neurointerventional procedures.

Mayo Clinic

Relievant Medsystems

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Relievant provides patients with low risk therapy that affords the ability to alleviate their back pain.

Mayo Clinic

Nuvaira

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Nuvaira is a new alternative COPD treatment option that specializes in developing devices for treating lung diseases.

Mayo Clinic

Recombinetics

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Recombinetics targets biomedical and regenerative medicine, opening vast new opportunities to improve and extend human life.

Mayo Clinic

Respicardia

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Respicardia develops implantable therapies to improve respiratory and cardiovascular health.

Mayo Clinic

HealthPartners

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HealthPartners is a nonprofit health care provider and health insurance company providing health care services and health plan financing.

Mayo Clinic

UnitedHealth Group

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UnitedHealth Group is a healthcare company that offers insurance products and services for everyone.

Mayo Clinic

EnteroMedics

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EnteroMedics® Inc. (NASDAQ: ETRM) is the developer of in-class weight loss treatments for obesity and obesity related risk factors.

Mayo Clinic

Conventus Orthopaedics

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Conventus Orthopaedics is a provider of a range of orthopedic and sports medicine services.

Mayo Clinic

StemoniX

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StemoniX is a biotechnology company that focuses on stem cell technologies to meet the demands of drug discovery and personalized medicine.

Mayo Clinic

NeoChord

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NeoChord is a medical device company that develops devices that allow mitral valve repair to be performed on a beating heart.

Mayo Clinic

NovuHealth

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NovuHealth is the leading healthcare consumer engagement company.

Mayo Clinic

4C Medical Technologies

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4C Medical Technologies is a medical device company that develops minimally invasive therapies for structural heart disease.

Mayo Clinic

Ativa Medical

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Ativa Medical is working to make diagnostic test results available in moments, rather than hours and days.

Mayo Clinic

Aria CV

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Aria CV is developing a medical device designed to improve the lives of patients living with the disease of pulmonary hypertension.

Mayo Clinic

Antares Pharma

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Antares Pharma is a revenue-generating product focused specialty pharmaceutical company

Mayo Clinic

Lifesprk

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Lifesprk is a hospital & health care company that offers home care management and senior living services.

Mayo Clinic

Biothera

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Biothera is a biotechnology company developing natural gluco polysaccharides that engage and direct natural innate immune systems.

Mayo Clinic

Humanetics Corporation

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clinical stage pharmaceutical company.

Mayo Clinic

NxThera

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NxThera develops medical technologies to treat a variety of endourology conditions, including BPH.

Mayo Clinic

Cardiovascular Systems

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Cardiovascular Systems develops and markets medical devices for the treatment of cardiovascular disease.

Mayo Clinic

Ambient Clinical Analytics

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Ambient Clinical Analytics is a provider of clinical analytics solutions to health systems and hospitals,

Mayo Clinic

Entellus Medical

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Entellus Medical develops technology-based treatment solutions for ENT physicians, their patients and payers.

Mayo Clinic

CHF Solutions

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CHF Solutions is a medical device company that focuses on innovative cardiac assist therapy to treat patients.

Mayo Clinic

Pops Diabetes Care

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Pops Diabetes Care offers a virtual healthcare platform to enable people to self-manage diabetes through consumer-centric sensors.

Mayo Clinic

RedBrick Health

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RedBrick Health, a health engagement and behavior-based technology company, helps organizations optimize their health and wellness programs.

Mayo Clinic

Abilitech Medical

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Abilitech Medical is a medical device company providing solutions for patients with neuromuscular conditions.

Mayo Clinic

Minnetronix

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We are a medical technology and innovation company with deep expertise in electronic and electromechanical devices.

Mayo Clinic

Healthsense

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Healthsense is a provider of aging services technology, offering technology-enabled care solutions for the senior care continuum.

Mayo Clinic

ABS

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ABS designs and develops minimally-invasive technology that focuses on relieving pain in the knee.

Mayo Clinic

Urotronic

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A Minnesota based, medical device company, making an exciting innovation in urethral stricture treatment.

Mayo Clinic

ShiraTronics

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ShiraTronics is in the early stages of developing new innovative therapies to combat debilitating migraine headache.

Mayo Clinic

Tactile Medical

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Tactile Medical develops medical devices that support the treatment of edema and vascular diseases at home.

Mayo Clinic

IMRIS Inc.

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IMRIS provides an image-guided therapy environment, facilitating timely information to clinicians to use during surgical procedures.

Mayo Clinic

Neuroone Medical Technologies

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NeuroOne is a medical technology company focused on improving surgical care for patients suffering from neurological disorders.

Mayo Clinic

Osprey Medical

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Osprey Medical develops and commercializes its propriety CINCOR™ System designed for the prevention of contrast induced mephropathy.

Mayo Clinic

Cardionomic

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Cardionomic is a medical device developer that treats reduced cardiac output.

Mayo Clinic

GeneMatters

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GeneMatters delivers genetic counseling services for hospitals, health networks, academic research centers, and genetic testing labs.

Mayo Clinic

Rotation Medical

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Rotation Medical develops treatments for rotator cuff disease by reversing disease progression and restoring long-term shoulder function.

Mayo Clinic

Spineology

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Spineology provides anatomy-conserving spine surgery technology solutions.

Mayo Clinic

Imbio

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Imbio develops medical imaging software solutions that save lives and reduce costs.

Mayo Clinic

Torax Medical

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Torax Medical develops an implantable device for the treatment of gastroesophageal reflux disease.

Mayo Clinic

Cogentix Medical

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Cogentix Medical products have increased treatment efficiency and lowered patient risk.

Mayo Clinic

Zyga Technology

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Zyga Technology is a surgical solutions provider developing & commercializing medical devices for treating spine problems.

Mayo Clinic

Venture Med Group

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VMG designs, develops which enable interventionalists to cost effectively treat peripheral artery diseases.

Mayo Clinic

ValenTx

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ValenTx is a development-stage medical device company that focuses on minimally-invasive methods for the treatment of morbid obesity.

Mayo Clinic

Cryosa

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CryOSA is a medical device company developing novel treatments for obstructive sleep apnea.

Mayo Clinic

Francis Medical

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Francis Medical is a Medical Technology Company.

Mayo Clinic

Reprise Biomedical

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Reprise Biomedical focuses on the development and commercialization of biological medical devices.

Mayo Clinic

SynerFuse

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SynerFuse is a provider of traditional spine implants intended to offer long-term pain management without the use of addictive opioids

Mayo Clinic

Murata Vios

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Murata Vios is a medical technology company developing wireless monitoring platform for intensive healthcare applications.

Mayo Clinic

CardiaLen

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CardiaLen develops and commercializes pain-free cardioversion therapies for atrial fibrillation.

Mayo Clinic

Mardil Medical

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Mardil Medical is a medical device company developing therapies for structural heart diseases and heart abnormalities.

Mayo Clinic

Interrad Medical

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Interrad Medical develops innovative medical devices for use in minimally invasive interventional and surgical procedures.

Mayo Clinic

MicroOptx

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MicroOptx is an early-stage medical device company that leverages academic bioengineering.

Mayo Clinic

Optum

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OptumInsight provides analytics, technology, and consulting services to improve the performance of health systems.

Mayo Clinic

Preceptis Medical

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Preceptis Medical develops surgical tools that allow ear tube procedures to be performed with less pain.

Mayo Clinic

Cardio Flow

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Cardio Flow is an early-stage development company with a new approach to orbital atherectomy.

Mayo Clinic

Tendyne Holdings

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Tendyne is a medical device company developing a transcatheter aortic valve implantation system.

Mayo Clinic

Elucent Medical

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Elucent Medical is a new idea in breast cancer treatment that exists to bring better healthcare ideas.

Mayo Clinic

Leafline Labs

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LeafLine Labs provides high quality medical cannabis and care to patients.

Mayo Clinic

Vergent Bioscience

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Vergent Bioscience is a biotech company leading the development of tumor-targeted molecular imaging molecules for cancer surgery.

Mayo Clinic

AUM Cardiovascular

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AUM Cardiovascular is a medical device manufacturing company that specializes in the fields of biotechnology, medical, and healthcare.

Mayo Clinic

Skyline Medical Inc.

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BioDrain Medical offers STREAMWAY System, a surgical fluid disposal device that eliminates exposure to blood and infectious fluids.

Mayo Clinic

Vertebral Technologies

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Vertebral Technologies is a medical device company that creates breakthrough implantable spinal devices.

Mayo Clinic

SpineThera

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SpineThera develops novel, sustained-release, injectable drugs to treat pain.

Mayo Clinic

ExceleraRx

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Excelera is a specialty pharmacy network helping members assert control over complex patient outcomes and total cost of care.

Mayo Clinic

EmStop

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EmStop engages in the medical devices business namely embolic protection devices.

Mayo Clinic

Thaddeus Medical

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Connected hardware to control and track temperature for sensitive medical products.

Mayo Clinic

Surgical Information Sciences

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Surgical Information Sciences is a healthcare Company.

Mayo Clinic

Augustine Temperature Management

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Augustine Temperature Management develops conductive fabric patient warming systems for surgical patients in the United States.

Mayo Clinic

CoraVie Medical Inc.

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Early stage med device co. developing a subcutaneous continuous blood pressure monitor for patients with uncontrolled hypertension.

Mayo Clinic

Stimdia Medical

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Stimdia Medical is a developer of a lung pacing device intended to facilitate weaning patients from mechanical ventilation.

Mayo Clinic

Nirva Medical

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Nirva Medical is a medical device start up focusing on organ-specific therapy-delivery technology for various clinical applications.

Mayo Clinic

Minnesota Medical Solutions

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Minnesota Medical Solutions is one of only two licensed medical cannabis manufacturers .

Mayo Clinic

MetaModix

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MetaModix manufactures surgical and medical instruments for the treatment of metabolic disease and Type II diabetes.

Mayo Clinic

Univita Health

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Univita Health provides home-based care management programs to improve patient outcomes and lower health care costs.

Mayo Clinic

Celleration

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Celleration is a medical device company developing and commercializing therapeutic ultrasound platforms.

Mayo Clinic

RoverMed BioSciences

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RoverMed has developed precision targeted nanocapsule technology aimed at delivering life saving drugs to the most challenging disease sites

Mayo Clinic

Cardia

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Cardia is an innovative company engaged in developing, manufacturing and marketing transcatheter septal occluders.

Mayo Clinic

NitriCap Medical

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NitriCap Medical develops a single-use antimicrobial catheter insert device to fight catheter-related bloodstream infections.

Mayo Clinic

Autonomix Medical

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Autonomix Medical is a developer of a novel technology designed to bring clarity to minimally invasive renal denervation.

Mayo Clinic

Ocudyne

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Ocudyne is based in Baltimore, Maryland.

Mayo Clinic

Alska

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Alska provides family caregivers with the ability to store, manage and share key information.

Mayo Clinic

Marblehead Medical

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Marblehead Medical is a developer of device intended to optimize the efficacy of mechanical thrombectomy.

Mayo Clinic

Novidan

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Novidan is designs, engineers and source products for the hard of hearing patient.

Mayo Clinic

SuperDimension

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SuperDimension is a medical device company developing minimally invasive pulmonology devices for the treatment of distal lung disease.

Mayo Clinic

St. Jude Medical

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St. Jude Medical develops medical technology and services that focus on putting more control into the hands of those who treat cardiac,

Mayo Clinic

Phraxis

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Phraxis is a medical device company developing solutions for patients who need vascular access to enable hemodialysis.

Mayo Clinic

Advanced Circulatory System

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Advanced Circulatory System manufactures and markets intrathoracic pressure regulation products.

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