Mark Smith
This article showcases our top picks for the best Maryland based Biotechnology companies. These startups and companies are taking a variety of approaches to innovating the Biotechnology industry, but are all exceptional companies well worth a follow.
We tried to pick companies across the size spectrum from cutting edge startups to established brands.
We selected these startups and companies for exceptional performance in one of these categories:
- Innovation
- Innovative ideas
- Innovative route to market
- Innovative product
- Growth
- Exceptional growth
- Exceptional growth strategy
- Management
- Societal impact
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Top Maryland Biotechnology Startups
Data sourced from Crunchbase and SemRush.
Novavax
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Novavax is a clinical-stage biotechnology company focused on the discovery and development of innovative vaccines.
Haystack Oncology
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Haystack Oncology enables precision oncology to optimize treatment strategies.
Arcellx
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Arcellx is a clinical-stage biotechnology company that provides patients with immune cell therapies.
Sirnaomics
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Sirnaomics is a biopharmaceutical company developing therapeutics for critical human diseases by using RNA interference technology.
National Institutes of Health
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National Institutes of Health is a biomedical research facility that focuses on biomedical and health-related research.
GeneDx
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GeneDx, a division of BioReference Laboratories, is a global industry in genetics and genomics, providing testing to patients and families.
b.well Connected Health
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b.well Connected Health provides an integrated solution for consumer engagement, holistic health management, and cost containment.
REGENXBIO
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REGENXBIO develops adeno-associated viral vector-based therapeutics and research tools, offering NAV, a recombinant AAV-vector.
Precision Medicine Group
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Precision Value & Health is engineered to bring expertise to every juncture of the innovation and commercialization continuum.
TissueGene
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TissueGene is a biopharmaceutical company focused on developing regenerative therapies for the treatment of various orthopedic disorders.
Emergent BioSolutions
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Emergent BioSolutions develops, manufactures, and delivers a portfolio of medical countermeasures for biological and chemical threats.
NextCure
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NextCure is a biopharmaceutical company focused on discovering and developing next generation immuno-oncology-based drugs.
OpGen
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OpGen is a precision medicine company utilizing molecular diagnostics and bioinformatics to help combat infectious disease.
Senseonics
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Senseonics is a medical device startup company that focuses on the design, development, and commercialization of glucose monitoring systems.
Adaptive Phage Therapeutics
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Adaptive Phage Therapeutics provides therapeutic services intended to treat multi-drug resistant pathogenic bacteria.
Precigen
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Precigen is a life sciences company researching and developing bio-therapeutic control systems to minimize toxicity.
Integrated BioTherapeutics
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Integrated BioTherapeutics focuses on the discovery of novel vaccines and therapeutics for emerging infectious diseases.
RoosterBio
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RoosterBio is a biotechnology company, offers synthetic biology and regenerative medicine.
Gain Therapeutics
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Gain Therapeutics is a biotech company developing pharmacological chaperones drugs designed to treat rare metabolic disorders.
Personal Genome Diagnostics
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Personal Genome Diagnostics develops a patient-specific analysis of the cancer genome by using advanced tools and technologies.
Precision for Medicine
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Precision for Medicine is a specialized scientific services company helping life science innovators develop medical products.
PaxVax
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PaxVax is a start-up developing candidate oral vaccines for key infectious diseases.
Supernus Pharmaceuticals
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Supernus Pharmaceuticals is focused on developing and commercializing products for the treatment of central nervous system.
ValenzaBio
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ValenzaBio is developing safe and effective treatment options for patients with autoimmune and inflammatory diseases.
NexImmune
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NexImmune is a biopharmaceutical company developing novel immuno-therapeutics based on the proprietary artificial immune technology.
American Gene Technologies International
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AGT is pioneering gene therapy solutions to achieve permanent cures for human diseases, including a possible cure for HIV in clinical trials
SalubrisBio
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SalubrisBio is a clinical-stage biotechnology company dedicated to discovering and developing novel antibody and protein-based therapeutics.
BrainScope Company
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Brainscope is a medical neurotechnology company that improves brain health.
Vita Therapeutics
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Vita Therapeutics is a cell engineering company that develops life-transformative treatments.
Aziyo Biologics
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Aziyo is a developer of customized tissue products intended to restore health and mobility to the greatest number of patients.
Sensei Biotherapeutics
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Sensei Biotherapeutics is a clinical-stage biotechnology company specializing in the field of next-generation cancer immunotherapies.
RNAimmune
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RNAimmune is a biopharmaceutical company specializing in the discovery and development of mRNA-based therapeutics and vaccines.
Previse
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Previse is a life sciences company focused on the development and commercialization of diagnostic tests for cancer prevention.
20/20 Gene Systems
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20/20 GeneSystems (‘20/20’) was founded in May of 2000 to develop and promote an innovative proteomics product line that provides drug
Osiris Therapeutics
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Osiris Therapeutics is a stem cell company, which focuses on developing and marketing products to treat medical conditions.
Altimmune
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Altimmune focused on the development of products to stimulate robust and durable immune responses for the prevention.
OncoImmune
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OncoImmune is a clinical-stage biopharmaceutical company that develops solutions for the treatment of cancer.
NeuralStem
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Neuralstem, a biotherapeutics company, aims to apply stem cell research and technology to treat diseases of the central nervous system.
GlycoMimetics
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GlycoMimetics is a biopharmaceutical company designing and developing small molecule therapeutics to treat various cancers.
Cartesian Therapeutics
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Pioneering Potent, Safer Cell Therapy in and Beyond Oncology
CSA Medical
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CSA Medical is a provider of innovative spray cryotherapy medical device solutions.
Northwest Biotherapeutics
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Northwest Biotherapeutics is a biotechnology company focused on developing and commercializing immunotherapy products to treat cancer.
VLP Therapeutics
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VLP is a biotech company with a mission to address unmet medical needs worldwide and expand the frontiers of vaccine treatment.
National Spine & Pain Centers
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National Spine & Pain Centers provides administrative services to interventional pain management clinics.
CoapTech
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CoapTech is an early-stage medical device company aiming to improve medical care delivery for patients young and old around the world.
MaxCyte
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MaxCyte specializes in cell modification technologies that enable the discovery, development, and manufacture of various classes.
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Sonavex is a developer of an imaging technology designed to visualize and quantify critical data to detect anastomotic blood clots.
RS BioTherapeutics
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RS BioTherapeutics is a research, development, and commercialization company focused on pulminary diseases.
BioFactura
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BioFactura is a biopharmaceutical research and manufacturing company
InventWood
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InventWood develops cellulose-based materials for environmental.
NeuroCytonix
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NeuroCytonix is a biomedical technology company that is centered on tissue creation and regeneration.
CellPhire
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Cellphire has developed a proprietary method for the stabilization of blood in the dry state
CASI Pharmaceuticals
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CASI focus on building a pipeline through mutually beneficial business development transactions.
Synthetic Biologics
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Synthetic Biologics is a biotechnology company developing biologics for the prevention and treatment of serious infectious diseases.
Ravgen
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Ravgen is a biotechnology company that specializes in non-invasive prenatal diagnostic testing.
TeraImmune
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Developer of cell therapeutics created for autoimmune diseases and immune-related disorders.
AsclepiX Therapeutics
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AsclepiX Therapeutics is a biotech company that develops novel therapeutics to revolutionize the treatment of retinal diseases and cancer.
Elixirgen Therapeutics
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Elixirgen Therapeutics is a biotechnology company focused on the development of therapies for genetic diseases and vaccines.
Veralox Therapeutics
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Veralox Therapeutics develops small molecule therapeutics that treat the underlying pathologies of thrombosis and type one diabetes.
Cerecor
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Cerecor discovers, develops and commercializes neuroscience drugs.
MyMD
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MyMD is a clinical-stage pharmaceutical company focused on the development of drug products.
Avalo Therapeutics
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Avalo Therapeutics is a clinical-stage biopharmaceutical company.
Seraxis
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Seraxis is a privately owned biotechnology company.
Origene Technologies
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OriGene Technologies is a research tool company that provides a commercial collection of full-length human cDNAs.
Nuo Therapeutics
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Nuo Therapeutics develops biological therapies to address the areas of wound care, inflammation, and angiogenesis.
Intralytix
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Intralytix is a biotechnology company focused on the discovery, production and marketing.
Delfi Diagnostics
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Delfi Diagnostics detects cancer early, when it is most curable, using high precision non-invasive blood tests.
miRecule
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MiRecule is an early-stage biotechnology company that focuses on developing microRNA-based therapeutics.
Vigene Biosciences
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Vigene develops gene delivery technologies with the mission to advance biomedical research and to make gene therapy affordable.
Gliknik
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Gliknik develops therapies for patients with cancer and immune disorders.
Remedy Plan Therapeutics
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Remedy Plan is a pre-clinical cancer therapeutics company developing first-in-class small molecule drugs that differentiate cancer cells.
NovaSom
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NovaSom provides obstructive sleep apnea home testing devices with cardio-respiratory monitoring ability.
CiVi Biopharma
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CiVi Biopharma is a clinical stage research and development biotechnology company whose mission is to create novel cardiovascular.
CosmosID
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CosmosID is a bioinformatics company focused on rapid identification of microorganisms in metagenomic samples.
Synaps Dx
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Synaps Dx focuses on the research, development and commercialization for neurodegenerative disorders including Alzheimer’s Disease.
VerImmune
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VerImmune is an Immuno-Oncology company developing a first-in-class cancer therapy known as Anti-tumor Immune Redirection.
RegeneRx
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RegeneRx is a biopharmaceutical company that designs, researches, and develops novel peptides targeted at diseases with unmet medical needs.
Glyscend
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Glyscend develops a revolutionary approach to treating type 2 diabetes.
Foundation Fighting Blindness
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The Foundation intends to provide preventions, treatments & cures for people affected by entire spectrum of retinal degenerative diseases.
Vaccinogen
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Vaccinogen manufactures vaccines and other immunotherapeutic products for cancers and infectious diseases.
Sisu Global Health
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Sisu is a medical device company that designs and commercializes medical devices with and for emerging markets.
Profectus Biosciences
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Profectus Biosciences is a R&D company developing vaccine and small molecules to treat and prevent viral diseases and cancers.
Lifesprout
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LifeSprout offers revolutionary products for soft tissue replacement and regeneration
HeMemics Biotechnologies, Inc.
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The company develops a low-cost biosensor platform with graphene-based sensors to detect multiple pathogens in one test within 2 minutes.
The Howard Hughes Medical Institute
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The Howard Hughes Medical Institute, a non-profit medical research organization, aims to advance biomedical research and science education.
Akonni Biosystems
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Akonni Biosystems is a biotechnology company that develops and manufactures, genetic testing devices.
Novel Microdevices
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Novel Microdevices is a medical device startup that develops a handheld point-of-care medical device to facilitate molecular diagnostics.
Breethe
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Breethe is a medical device company that develops a compact artificial lung for patients with acute and chronic lung problems.
Cytimmune Sciences
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CytImmune Sciences focuses on the discovery, development and commercialization of multifunctional, tumor-targeted therapies.
Silvec Biologics
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Silvec Biologics offers therapy for trees using RNA-based molecules.
RevivBio
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RevivBio is a biotechnology company that focuses on microbial innovation.
Shuttle Pharmaceuticals
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Shuttle Pharmaceuticals is a clinical-stage pharmaceutical company utilizing proprietary technology to develop novel therapies.
Minnowtech
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Minnowtech develops aquaculture technologies to maximize aquafarmers’ cultivation efforts using integrated sensor-based systems.
Clear Guide Medical
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Clear Guide Medical is a privately-held company
AAVogen
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AAVogen is a biotech startup that develops gene therapeutics for muscle wasting diseases.
RLL
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RLL LLC is a biotechmology company that researches and manufactures high quality phytochemicals and extracts worldwide.
SynerGene Therapeutics
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SynerGene Therapeutics is a biotechnology company with focuses on developing gene-based nanotech cancer therapeutics and diagnostics.
J. Craig Venter Institute
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J. Craig Venter Institute is a non-profit organization engaged in the research of genomics.
Vixiar Medical
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Vixiar Medical develops non-invasive, cost-effective devices and systems for monitoring cardiopulmonary diseases.
