Mark Smith
This article showcases our top picks for the best Massachusetts based Biotechnology companies. These startups and companies are taking a variety of approaches to innovating the Biotechnology industry, but are all exceptional companies well worth a follow.
We tried to pick companies across the size spectrum from cutting edge startups to established brands.
We selected these startups and companies for exceptional performance in one of these categories:
- Innovation
- Innovative ideas
- Innovative route to market
- Innovative product
- Growth
- Exceptional growth
- Exceptional growth strategy
- Management
- Societal impact
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Top Massachusetts Biotechnology Startups
Data sourced from Crunchbase and SemRush.
Ginkgo Bioworks
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Ginkgo Bioworks is a developer of biological engineering products and custom microbes across multiple markets.
Thermo Fisher Scientific
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Thermo Fisher Scientific is a science and pharma service provider of laboratory information management & scientific data systems.
Biobot Analytics
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Biobot Analytics is a wastewater epidemiology company that is transforming wastewater infrastructure into public health observatories.
Pear Therapeutics
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Pear Therapeutics is a software-based digital therapeutics platform designed to treat disease and enhance the efficacy of pharmaceuticals.
Intellia Therapeutics
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Intellia Therapeutics is a genome editing company that develops curative gene-editing treatments.
CRISPR Therapeutics
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CRISPR Therapeutics is focused on the development of transformative medicines using its proprietary CRISPR/Cas9 gene-editing platform.
Neumora Therapeutics
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Neumora Therapeutics operates as a clinical-stage biotechnology company.
Biofourmis
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Biofourmis is a biotechnology company that augments personalized care and therapies using digital therapeutics.
SOPHiA GENETICS
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SOPHiA GENETICS is a biotechnology firm that aims to support healthcare professionals by maximizing the power of data-driven medicine.
Catalog
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Catalog is a developer of a data conversion and storage platform used to offer the next generation of digital data archives.
Relay Therapeutics
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Relay therapeutics is a developer of an allosteric drug-discovery platform intended to apply computational techniques to protein motion.
EQRx
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EQRx is a biotechnology company that focuses on re-engineering the process of drug discovery to make them affordable.
Synlogic
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Synlogic is a biotechnology company that develops synthetic biotic medicines to perform metabolic functions to treat diseases.
Valo Health
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Valo Health uses human-centric data and machine learning-anchored computation to transform the drug discovery and development process.
Pyxis Oncology
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Pyxis Oncology is a developer of antibody therapeutics intended to promote the body’s immune response to cancer.
Cedilla Therapeutics
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Cedilla Therapeutics is a biotechnology company that develops targeted small molecules for the treatment of cancer and other diseases.
Centessa Pharmaceuticals
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Centessa Pharmaceuticals is a next-generation biopharmaceutical company that aims to reshape the traditional drug development process.
Beam Therapeutics
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Beam Therapeutics is a biotechnology company developing precision genetic medicines through the use of base editing technology.
nference
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nference.inc, provides an AI based software platform that synthesizes siloed biomedical knowledge for insights and makes it computable.
Editas Medicine
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Editas Medicine is engaged in discovering and developing a novel class of genome editing therapeutics.
Xilio Therapeutics
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Xilio Therapeutics is a biopharmaceutical company focused on developing highly-potent, targeted immuno-oncology therapeutics.
Moderna Therapeutics
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Moderna Therapeutics is a biotechnology company that specializes in drug discovery and drug development based on messenger RNA.
Sarepta Therapeutics
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Sarepta Therapeutics focuses on the discovery and development of precision genetic medicine to treat rare diseases.
Invaio Sciences
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Invaio Sciences is a technology company that is dedicated to solving pressing agriculture, nutrition, and environmental challenges.
Stealth BioTherapeutics
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Stealth BioTherapeutics is a clinical-stage biotechnology company focused on the discovery and commercialization of novel therapies.
Delix Therapeutics
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Delix Therapeutics is a CNS-focused drug discovery company.
Akili Interactive Labs
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Akili builds clinically-validated cognitive therapeutics, assessments, and diagnostics that look and feel like video games.
Spero Therapeutics
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Spero Therapeutics is developing first in class therapeutics for treatment of Gram-negative infections.
Exo Therapeutics
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Exo Therapeutics is a small molecule drug discovery and development company.
Acceleron Pharma
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Acceleron is a biopharmaceutical company engaged in developing, manufacturing and commercializing novel biotherapeutics.
ConcertAI
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ConcertAI is an AI-powered SaaS data company in healthcare that develops medical research tool in oncology.
Intergalactic Therapeutics
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Intergalactic Therapeutics is an ATP company, is revolutionizing gene therapies with a novel non-viral platform.
Akoya Biosciences
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Akoya Biosciences is a spatial biology company offering solutions for high-parameter tissue analysis from biomarker discovery to validation.
SeLux Diagnostics
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SeLux Diagnostics is a developer of the next-generation phenotyping platform that enables personalized antibiotic therapies for patients.
Voyager Therapeutics
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Voyager Therapeutics is a gene therapy company developing treatments for fatal and debilitating diseases of the central nervous system
Laronde
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Laronde develops an eRNA-based therapeutic platform that is capable of indicating diverse proteins inside the body.
Finch Therapeutics
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Finch Therapeutics is a microbiome development company that serve patients with serious unmet medical needs.
Axial Therapeutics
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Axial Therapeutics is a clinical stage biopharmaceutical company harnessing the gut-brain axis to develop novel Central Nervous System.
TetraScience
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TetraScience is an R&D cloud data management company that empowers transformation in life sciences and drug discovery.
Bluebird Bio
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Bluebird Bio offers products based on the transformative potential of gene therapy for patients with genetic and orphan diseases.
Agenus
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Agenus develops and commercializes immunotherapies and vaccines for cancer and infectious diseases.
Motif
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Motif makes ingredients for the next generation of plant-based and healthy foods.
Skyhawk Therapeutics
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Skyhawk Therapeutics is a provvider of small molecule therapeutics designed to offer therapies that correct RNA expression.
Repligen
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Repligen is a biopharmaceutical company developing consumable products for the manufacture of biological drugs.
Obsidian Therapeutics
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Obsidian Therapeutics is a developer of a next-generation cell and gene therapies created to extend adoptive immunotherapy.
Charles River Laboratories International
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Charles River Laboratories International provides research models, and outsourced preclinical services for the accelerated R&D of drugs
Quanterix
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Quanterix is a platform for single molecule analysis that supports clinical diagnostics, drug development, and life science researches.
Scipher Medicine
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Scipher Medicine develops a healthcare platform designed to determine which drug will work best for each patient.
Kytopen
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Kytopen developer of a cell therapy platform for non-viral delivery of molecules into hard-to-transfect immune cells.
Flexion Therapeutics
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Flexion Therapeutics is a biotechnology company that develops long-lasting intra-articular injection therapies to treat osteoarthritis.
Stoke Therapeutics
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Stoke is developing antisense oligonucleotide medicines that target RNA splicing to increase gene expression for the treatment.
Rectify Pharmaceuticals
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Rectify Pharmaceuticals is a biotechnology company developing Positive Functional Modulators (PFMs), disease-modifying therapeutics.
Vedanta Biosciences
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Vedanta Biosciences is a developer of immunotherapies designed to treat immune-mediated and infectious diseases.
Verve Therapeutics
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Verve is focused on discovering and developing therapies that safely edit the genomes of adults to confer protection against coronary.
RedShift BioAnalytics
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RedShift BioAnalytics is a developer and manufacturer of bioanalytical tools for the life science market.
T2 Biosystems
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T2 Biosystems develops a medical diagnostic platform that enables rapid and accurate diagnostic tests of all types on a single instrument.
Tango Therapeutics
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Tango Therapeutics is a biotechnology company that is developing next generation cancer therapies.
XtalPi
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XtalPi is a biotech firm that uses artificial intelligence and computing to accelerate the development of new pharmaceutical drugs.
Amylyx Pharmaceuticals
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Amylyx Pharmaceuticals specializes in providing solutions for Alzheimer’s and other diseases of the brain.
Inari
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Inari presents high performing plant varieties that improve the economic and environmental realities of production agriculture.
SAGE Therapeutics
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SAGE Therapeutics develops and delivers novel medicines for most debilitating and disabling central nervous system disorders.
ElevateBio
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ElevateBio is a biotechnology company that specializes in cell and gene-based therapies.
Translate Bio
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Translate Bio is a biotechnology company that specializes in biotechnology, RNA therapeutics, and rare diseases.
TScan Therapeutics
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TScan Therapeutics is a biopharmaceutical company focused on the development of immunotherapy treatments for cancer.
1910 Genetics
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1910 Genetics is a biotechnology company integrating AI, computation, and biological automation to improve drug development.
Foundation Medicine
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Foundation medicine is a molecular information company developing clinical diagnostic tests that facilitates personalized cancer therapies.
Alnylam Pharmaceuticals
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Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization.
Organogenesis
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Organogenesis Inc. is a regenerative medicine company.
YourBio Health
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YourBio Health optimizes the interface of diagnostic medicine and healthcare consumer by simplifying blood sampling and testing.
Eloxx
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Eloxx Pharmaceuticals is a clinical-stage biopharmaceutical company developing novel RNA-modulating drug candidates.
Thrive Earlier Detection
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Thrive Earlier Detection is a healthcare company that integrates earlier cancer detection into routine medical care.
Prime Medicine
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Prime Medicine operates as a biotechnology company.
Nimbus Therapeutics
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Nimbus Discovery is now Nimbus Therapeutics to reflect our transition into a clinical stage company.
Blueprint Medicines
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Blueprint Medicines engages in the discovery and development of highly selective kinase inhibitors for genomically defined cancer subsets.
EGenesis
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EGenesis focuses on leveraging genome editing technology to deliver safe and effective human transplantable cells, tissues, and organs.
Wave Life Sciences
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WaVe Life Sciences specializes in the development of next-generation nucleic acids for therapeutic and diagnostic applications.
Cerevel Therapeutics
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Cerevel Therapeutics is a biopharmaceutical company.
MOMA Therapeutics
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MOMA Therapeutics operates as a biotechnology company.
Elevian
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Elevian develops medicines that restore youthful regenerative capacity with the potential to treat and prevent many age-related diseases.
Lyndra Therapeutics
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Lyndra Therapeutics is a novel technology platform reinventing medicine for a healthier world.
Repertoire Immune Medicines
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Repertoire Immune Medicines is a clinical stage biotechnology company.
Gemini Therapeutics
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Gemini Therapeutics focuses on genetically-defined dry age-related macular degeneration (AMD) and associated rare genetic diseases.
SQZ Biotech
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SQZ Biotech features a cell engineering technology designed to deliver a diverse set of materials into patient cells.
Ribon Therapeutics
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Ribon Therapeutics is a biotechnology company focused on the development of therapeutics treatments targeting stress support pathways.
Solid Biosciences
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Solid Biosciences is a life science company that conducts research for the treatment of Duchenne muscular dystrophy (DMD).
Dyne Therapeutics
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Dyne Therapeutics is a developer of targeted therapies intended for serious muscle diseases.
Apellis Pharmaceuticals
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Apellis Pharmaceuticals focuses on developing novel therapeutics and drug delivery technologies to address chronic inflammatory diseases.
Cellarity
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Cellarity’s platform digitizes the molecular information in cells to elucidate how they behave in health and disease.
Rapid Micro Biosystems
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Rapid Micro Biosystems offers tools that detect microbial contamination in manufacturing pharmaceutical, biotechnology and other products.
Kymera Therapeutics
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Kymera Therapeutics is a biotechnology company that specializes in the field of targeted protein degradation.
Seres Therapeutics
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Seres Therapeutics is a microbiome therapeutics company focused on discovering and developing Ecobiotic therapeutic products.
Mersana Therapeutics
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Mersana Therapeutics develops a biodegradable polymer platform Fleximer® which creates new and better medicines.
Ocular Therapeutix
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Ocular Therapeutix develops and commercializes ophthalmic therapeutic products by using hydrogel technology.
Tarveda Therapeutics
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Tarveda Therapeutics is a developer of miniature drug conjugates designed for the treatment of patients with a wide range of solid tumors.
Alloy Therapeutics
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Alloy Therapeutics is a biotech company that makes medicine by democratizing access to foundational drug discovery platforms and services.
Magenta Therapeutics
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Magenta Therapeutics is a new biotechnology company developing therapeutics that unlock the power of stem cell biology.
Dyno Therapeutics
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Dyno Therapeutics is a biotechnology company that uses artificial intelligence for gene therapy.
Ring Therapeutics
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Ring Therapeutics company focused on discovering and developing Anellovector therapeutics to unlock the full potential of gene therapy.
Rhythm Pharmaceuticals
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Rhythm is a biopharmaceutical company focused on developing and commercializing peptide therapeutics
KSQ Therapeutics
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KSQ Therapeutics is using CRISPR technology within a powerful drug discovery engine to enable high-confidence drug development.
Manus Bio
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Manus Bio makes nature accessible and affordable for a growing society.
