101 Best Ohio Non Profit Companies and Startups

September 7, 2021
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This article showcases our top picks for the best Ohio based Non Profit companies. These startups and companies are taking a variety of approaches to innovating the Non Profit industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

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Top Ohio Non Profit Startups

Data sourced from Crunchbase and SemRush.

Cleveland Clinic

Cleveland Clinic

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Cleveland Clinic is a non-profit medical center that combines clinical and hospital care with research and education.

Big Lots

Big Lots

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Big Lots is a discount retailer that offers affordable solutions in the merchandise categories such as furniture, food, decor, and more.

Big Lots

Initiate Studios

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Initiate Studios is a creative programming and design outreach start-up studio.

Big Lots

FrontLine Service

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FrontLine Service is a private non-profit community.

Big Lots

The Dayton Foundation

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The Dayton Foundation, a community foundation, supports users to help people in the Greater Dayton region.

Big Lots

PlayhouseSquare

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PlayhouseSquare is a performing arts center.

Big Lots

The Cleveland Foundation

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The Cleveland Foundation is a community foundation in the U.S.

Big Lots

Dayton RTA

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The Greater Dayton RTA is the public transit agency that citizens count on in Montgomery County and western Greene County.

Big Lots

Lake Health

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Lake Health is a private, not-for-profit leader in community health care.

Big Lots

VeloSano

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VeloSano is more than a fundraising event. It’s more than simply a bike ride

Big Lots

Kids Read Now

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Kids Read Now is a non-profit organization designed to eliminate the summer reading slide for hundreds of schools from coast to coast.

Big Lots

The Greater Cincinnati Foundation

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The Greater Cincinnati Foundation helps people make the most of their giving to build a better community.

Big Lots

Big River

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Big River helps nonprofit organizations raise money by engaging donors through cloud-based targeting, promotions and social marketing.

Big Lots

CareSource

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CareSource is a leading non-profit public sector managed care company

Big Lots

Lake Erie Energy Development Corp

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Lake Erie Energy Development Corp is a financial development agency that provides wind energy, community outreach.

Big Lots

Akron Community Foundation

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They embrace and enhance the work of charitable people who make a permanent commitment to the good of the community.

Big Lots

Youngstown State University Foundation

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Youngstown State University Foundation is an independent, non-profit organization

Big Lots

Mercy Health

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Mercy Health is a mission-driven, integrated healthcare organization.

Big Lots

BRITE Energy Innovators

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BRITE empowers founders to launch energy technology solutions through entrepreneurial guidance and support services.

Big Lots

HCDC

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Hamilton County Business Center is a business incubation program helping entrepreneurs in Greater Cincinnati build successful companies.

Big Lots

Sisters of Charity Foundation of Cleveland

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The foundation works to end homelessness in Cuyahoga County and to reduce health and education disparities .

Big Lots

Mahoning Valley Economic Development Corporation

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Mahoning Valley Economic Development Corporation is a non-profit economic development corporation.

Big Lots

Saint Luke’s Foundation

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Saint Luke’s Foundation is dedicated to improving and transforming the health and well-being of individuals, families and communities.

Big Lots

Eastgate Regional Council of Governments

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Eastgate Regional Council of Governments is a voluntary association of local governments.

Big Lots

Central Clinic Behavioral Health

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Central Clinic Behavioral Health provides mental health services.

Big Lots

GiveNext

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GiveNext is an online platform that enables donors and non-profits to track and manage their charitable contributions.

Big Lots

SunDown RunDown Group

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SunDown RunDown hosts monthly business pitch events for entrepreneurs, classes, workshops, mentors, and access to capital

Big Lots

Donor Drive

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Donor Drive is the fundraising platform for enterprise nonprofits to create better fundraising experiences.

Big Lots

Dynamic Catholic

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Dynamic Catholic offers spiritual development resources, evangelization resources, and Video-based email programs.

Big Lots

TQL

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TQL is one of the largest 3PLs in North America. They arrange the movement of more than 20,000 loads of freight per week.

Big Lots

Nightlight Cinema

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Nightlight Cinema is an independent, nonprofit movie theater. Advancing cinema and community in tandem.

Big Lots

Walnut Hills Redevelopment Foundation

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Walnut Hills Redevelopment Foundation is a a non-profit community development corporation .

Big Lots

Interfaith Hospitality Network

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Interfaith Hospitality Network is a non profit organisation that provides homeless families emergency shelter and hospitality.

Big Lots

Lutheran Social Services

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Lutheran Social Services is a (LSS) helps thousands of people in need throughout 27 Ohio counties.

Big Lots

Mission Essential Personnel

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Mission Essential is a global services and solutions provider to the defense and intelligence communities.

Big Lots

Lydia’s House

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Lydia’s House provides housing for women and their young children.

Big Lots

Wright-Patt Credit Union

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Wright-Patt Credit Union is a not-for-profit member-owned financial institution.

Big Lots

Ingage Partners, LLC

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Ingage Partners was founded to Inspire and Engage people to blend their professional lives with their desire to better our communities.

Big Lots

Genesis HealthCare System

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Genesis HealthCare System operates with a mission to provide quality healthcare for cancer, heart and vascular, surgical and orthopedics.

Big Lots

Clearview Federal Credit Union

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Clearview Federal Credit Union is a non-profit financial service company that offers loans, credit cards, mortgages and banking solutions.

Big Lots

STRS Ohio

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STRS Ohio is one of the nation’s premier retirement systems, serving nearly a half million active and retired Ohio public educators.

Big Lots

Pro Football Hall of Fame

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Honor the Heroes of the Game, Preserve its History, Promote its Values & Celebrate Excellence EVERYWHERE.

Big Lots

Corporate One

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Corporate One provides cash management, liquidity, investments and digital payment solutions to credit unions.

Big Lots

Battelle for Kids

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Battelle for Kids is a non-profit organization helps teachers and leaders to improve school systems.

Big Lots

Unify Labs

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Unify Labs is a nonprofit tech innovation center that transforms the hiring experience fo job seekers and employers.

Big Lots

Collective Health

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Collective Health is to improved upstream health factors that drive more than half of downstream illness and costs.

Big Lots

Equitas Health

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Equitas Health specializes in LGBTQ healthcare, advocacy, dentistry, transgender care, pharmacy, wellness and HIV/STI prevention services.

Big Lots

Day Air Credit Union

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Day Air Credit Union is a nonprofit organization that offers financial services.

Big Lots

Fidelity Charitable

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Since 1991, Fidelity Charitable has helped donors support over 190,000 nonprofit organizations with more than $19 billion in grants.

Big Lots

General Electric Credit Union

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General Electric Credit Union offers investment, real estate, legal, financial, identity theft and debt management services.

Big Lots

Drund

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Drund is a private communications platform enabling nonprofits, education institutions and families to safely share information.

Big Lots

The Rock and Roll Hall of Fame and Museum

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Is the nonprofit organization that exists to educate visitors, fans and scholars from around the world.

Big Lots

Wilson Health

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Wilson Health is a healthcare system and hospital that renders comprehensive health care services to patients.

Big Lots

Federation of State Boards of Physical Therapy

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Federation of State Boards of Physical Therapy focuses on providing services that help incompetent physical therapy practice.

Big Lots

Recovery Resources

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Recovery Resources is a nonprofit organization that provides behavioral health and addiction services.

Big Lots

Jani-King of New Orleans

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Jani-King is one of the world’s most inspiring companies and truly represents entrepreneurial spirit.

Big Lots

Safecare

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Safecare is a web-based screening service that monitors nurses’ aides and reports any act of abuse or criminal activities.

Big Lots

OKI Regional Council of Governments

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OKI Regional Council of Governments is a panel with a common objective of developing unified strategies to improve the quality of life.

Big Lots

Sun Federal Credit Union

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Sun Federal Credit Union is a full-service financial firm that serves sponsor groups and designated communities.

Big Lots

Wood County Hospital

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Wood County Hospital is a not-for-profit hospital that is dedicated to comprehensive healthcare and emergency services.

Big Lots

NorTech

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NorTech is a technology-focused organization.

Big Lots

Ohio University Credit Union

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Ohio University Credit Union is a not-for-profit financial cooperative focused on improving the financial well being of members.

Big Lots

Wayne HealthCare

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Wayne HealthCare is a non-profit hospital that delivers complete healthcare and emergency services.

Big Lots

Greater Cincinnati Behavioral Health Services

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Greater Cincinnati Behavioral Health Services is a mental health services agency.

Big Lots

Cuyahoga County Public Library

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Cuyahoga County Public Library provides knowledge online with a digital collection of books and mobile printing as well as photo services.

Big Lots

Wingspan Care Group

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Wingspan Care Group is a non-profit administrative and management organization that provides a united community-based network of services.

Big Lots

Ohio Hospital Association

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Ohio Hospital Association engaged in the collaboration with member hospital and health systems to enhance the well being of the residents.

Big Lots

National Business Incubation Association

Crunchbase Website Twitter Facebook Linkedin

National Business Incubation Association

Big Lots

OPC Foundation

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The OPC Foundation is dedicated to ensuring interoperability in automation.

Big Lots

Fairfield Medical Center

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FMC is a hospital & healthcare specializes in provides efficient, high quality healthcare for patients and their families.

Big Lots

Ohio’s Hospice

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Ohio’s Hospice is an NGO that renders superior care, hospitality, medical, patient and healthcare services for communities.

Big Lots

Koinonia Homes

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Koinonia Homes is a non-profit organization that provides services for people with intellectual and developmental disabilities.

Big Lots

COSI

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Center of Science and Industry in Columbus, OH

Big Lots

Ohio Catholic Federal Credit Union

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Ohio Catholic Federal Credit Union is a nonprofit financial services provider company.

Big Lots

Education First Credit Union

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Education First Credit Union serves the education community.

Big Lots

Team NEO

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Team NEO is an economic development organization focused on creating jobs

Big Lots

Otterbein

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Otterbein specializes in offering a wide range of assisted living, rehabilitation, nursing care and home health care services.

Big Lots

Women’s Small Business Accelerator

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Women’s Small Business Accelerator was formed to help all women business owners.

Big Lots

Jeffrey Thomas Hayden Foundation

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The Jeffrey Thomas Hayden Foundation is a registered 501(c)3 non-profit organization founded in September 2004.

Big Lots

Columbus Partnership

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The Columbus Partnership is a non-profit, membership-based CEO organization.

Big Lots

Clovernook

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Clovernook is a non-profit organization that empowers people who are blind and visually impaired to be self-sufficient in their communities.

Big Lots

Education at Work

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Education at Work is an outsourcing company that helps college students to secure their finances by rendering job opportunities.

Big Lots

The Columbus Association For The Performing Arts

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CAPA is a non-profit, award-winning performing arts organization, presenting national and international performing arts and entertainment.

Big Lots

Lima Memorial Health System

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Lima Memorial Health System offers primary care, pediatric, telehealth, women’s health, neonatal, home healthcare & rehabilitation services.

Big Lots

Genfed Financial Credit Union

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Genfed Financial Credit Union offers savings, loans, credit cards, mortgages, online banking and financial servcies.

Big Lots

Dayton Development Coalition

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Dayton Development Coalition is the regional economic development and advocacy organization.

Big Lots

Ohio Capital Corporation for Housing

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Ohio Capital Corporation for Housing is a non-profit organization that provides economic growth and affordable housing opportunities.

Big Lots

Health Recovery Services

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Health Recovery Services is a drug addiction treatment center that provides education, prevention, treatment and other supportive services.

Big Lots

Ohio Farm Bureau Federation

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The Ohio Farm Bureau Federation is a social organization that focuses on supporting agriculture and states food and farm communities.

Big Lots

Apprisen

Crunchbase Website Twitter Facebook Linkedin

Apprisen is a platform that specializes in offering a wide range of services to its clients to achieve their financial health and wealth.

Big Lots

Greater Cleveland Food Bank

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Greater Cleveland Food Bank works with individuals and food manufacturers to distribute free food to schools, daycares & emergency shelters.

Big Lots

Summit Academy Management

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Summit Academy Schools, a network of K-12 tuition-free, non-profit public schools that compassionately serve students who learn differently.

Big Lots

Ohio Environmental Protection Agency

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Ohio Environmental Protection Agency protects the environment and public health.

Big Lots

Uct Property Inc.

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UCT is a non-profit financial services membership organization based in Columbus, Ohio.

Big Lots

TCN Behavioral Health Services

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TCN Behavioral Health Services is a mental health care center that expertise in behavioral health, psychiatry and prevention services.

Big Lots

The American Society for Nondestructive Testing

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The American Society for Nondestructive Testing is the technical society for nondestructive testing professionals.

Big Lots

The Center for Health Affairs

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The Center for Health Affairs is a nonprofit organization that helps in the healthcare industry.

Big Lots

Cornucopia, Inc.

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Cornucopia is a nonprofit organization that helps people with disabilities develop skills and confidence leading to sustainable employment.

Big Lots

The Ohio Masonic Home

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The Ohio Masonic Home provides family and community resources such as nursing care, assisted living, rehabilitation and therapy.

Big Lots

Emery Federal Credit Union

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Emery Federal Credit Union is a not-for-profit financial cooperative.

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