101 Top San Francisco B2B Companies and Startups of 2021

June 18, 2021
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This article showcases our top picks for the best San Francisco based B2B companies. These startups and companies are taking a variety of approaches to innovating the B2B industry, but are all exceptional companies well worth a follow.

We tried to pick companies across the size spectrum from cutting edge startups to established brands.

We selected these startups and companies for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

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Top San Francisco B2B Startups

Data sourced from Crunchbase and SemRush.

Shippo

Shippo

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Shippo is a shipping platform that helps e-commerce companies manage their shipping operations more seamlessly.

Magic

Magic

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Magic provides a 24/7 SMS based on-demand personal assistant service.

Magic

Fundbox

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Fundbox is an AI-powered financial platform for small businesses.

Magic

Sendoso

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Sendoso helps companies connect and drive revenue with personalized gifts, eGifts, virtual experiences, and more.

Magic

Zumper

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The third largest rental platform in North America—supporting over 90m people every year and helping 1 in 3 Americans find their next place.

Magic

Resolve

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Resolve is a B2B payments platform that offers buy now, pay later billing for business purchases.

Magic

Prodigy

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Prodigy digitizes the process to save customers’ time while improving trust and satisfaction.

Magic

HelloSign

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HelloSign offers fast, secure, and legally binding eSignatures for businesses.

Magic

Leadspace

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Leadspace is a B2B customer data platform that drives personalized customer engagement for sales and marketing.

Magic

Bugsnag

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Bugsnag provides an automated crash detection platform for web and mobile applications.

Magic

Wizeline

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Wizeline is a product design and development services company that builds data-driven, cloud-native products and platforms for its clients.

Magic

Metadata

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The autonomous demand generation platform for B2B enterprises.

Magic

Inscribe

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Inscribe helps companies detect fraudulent documents so they can trust their customers and grow faster.

Magic

BuyerAssist.io

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Buyerassist enables the revenue teams to deliver superior buyer experiences by helping them understand and deliver on customers’ priorities.

Magic

Jirav

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B2B Financial Modeling, FP&A, and Predictive Analytics

Magic

UpCounsel

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UpCounsel operates an online marketplace for businesses to find and hire legal help based on their preferences in the United States.

Magic

Simplified

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Simplified helps you design everything, scale your brand, and collaborate with your team like never before.

Magic

Plate IQ

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Plate IQ saves restaurants time and money by automating their invoice processing and accounts payable.

Magic

Instapage

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Instapage is a landing page platform designed to scale marketing efforts while lowering the costs.

Magic

Mutiny

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Mutiny helps you turn your website into your #1 sales channel, by personalizing your website for each visitor without any engineering work.

Magic

Rentberry

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Rentberry is a rental service platform that provides rental and price negotiation services to tenants and landlords.

Magic

COR

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COR is the next-generation solution that intelligently suggests how to manage your projects, teams, and finances.

Magic

Radius Intelligence

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Radius Intelligence seeks to power data intelligence across all B2B applications, channels, and users.

Magic

NewCo

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NewCo is an organizer of forums and conferences used to connect people with businesses on a mission.

Magic

Calixa

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Calixa is Customer Ops Platform for SaaS companies. It enables teams to understand customers and take action all in one place.

Magic

Miro

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Miro is an online collaborative whiteboard platform that enables distributed teams to work better together.

Magic

Growbots

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Growbots develops AI based platform for automating the outbound sales process.

Magic

Moov

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Moov is a software platform for buying and selling preowned manufacturing equipment.

Magic

RevOps

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RevOps, a CPQ company made for Software Businesses, helps Sales close deals faster with automation in the buying process.

Magic

Qualified.com

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Qualified.com is a B2B marketer that allows buyers and sales reps to connect through real-time website conversations.

Magic

2ndKitchen

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2ndKitchen enables businesses without a kitchen to serve food seamlessly using a custom menu from nearby restaurants.

Magic

Rentlytics

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Rentlytics is building the platform to transform the world’s real estate data into accessible information.

Magic

Genus AI

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Genus AI is a Growth Platform for D2C brands, helping them acquire, engage and retain their customers

Magic

Datch

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Datch operates as an intelligent voice interface for industrial environments.

Magic

Obe

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Digital Health Platform for Pet Parents and Veterinarians

Magic

Polytomic

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Sync internal data to your business systems

Magic

LocateAI

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LocateAI is using geospatial data and machine learning to transform the antiquated, $4T real estate industry.

Magic

Hostfully, Inc.

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Making vacation rentals easier to book and more fun to stay in.

Magic

Xola

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Booking Software for Tour and Activity Companies

Magic

Bizo

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Bizo is a marketing platform enabling B2B marketers to identify, reach and engage their target audiences online.

Magic

Sourcery Technologies

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Digital payments for the $220B wholesale food industry

Magic

Via.Delivery

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Integrating e-commerce parcels into brick and mortar supply chain to deliver locally at a fraction of the cost of traditional carriers

Magic

Platform Good

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Change platform linking fitness activities to charitable giving for consumers and solving CSR and marketing challenges for companies.

Magic

Woo.io

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Woo connects candidates who are discreetly exploring new opportunities to companies with the right job for them.

Magic

Euclid

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Euclid is a spatial analytics platform that uses WiFi signals to understand how people relate to spaces and how spaces relate to each other.

Magic

Tradeshift

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Tradeshift is a cloud-based business network connecting buyers and suppliers.

Magic

Queue

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Queue is a platform that lets creative professionals manage their clients, get feedback on their work, and get paid faster.

Magic

Social Construct

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Social Construct is a startup that is pioneering new technologies to deliver better housing.

Magic

Ravacan

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Ravacan is a Purchasing & Procurement software for commodity & supply managers, with a central place to analyze costs and manage suppliers.

Magic

Settle

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Settle is a fintech platform that automates B2B payments and provides working-capital solutions for businesses.

Magic

Boost Media

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Boost Media is a startup that uses crowdsourcing and split testing to help businesses find effective words and images for their online ads.

Magic

Upcall

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Upcall is the human-powered outbound sales & marketing calling platform.

Magic

Remedly

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Optimizing Operations of Medical Clinics With Specialty ERP Software

Magic

Arena.im

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Arena.im is a real-time content platform for media companies. Discover, curate and distribute content to increase engagement and drive sales

Magic

MightySignal

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MightySignal is a mobile application index that enables businesses to make sense of data patterns generated by mobile app companies.

Magic

Cred

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Cred is a lending ecosystem that facilitates open access to credit anywhere and anytime based on the Ethereum blockchain.

Magic

Cantaloupe Systems

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Cantaloupe Systems provides fully integrated IoT and SaaS solution for logistics management and cashless payment for unattended retail

Magic

Cloverpop

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Cloverpop’s enterprise platform is the way to keep track of decisions in Slack. Make better decisions 2x faster with 100 percent visibility.

Magic

Eze

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Eze is a B2B marketplace for electronics allowing buyers & sellers to trade in wholesale quantities with real-time market data.

Magic

LEAD

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Keep your workforce connected, build meaningful connections among employees. The best AI-powered employee matching software.

Magic

Sendbloom

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Tailored outbound messaging for sales

Magic

Torpago

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Torpago is a financial technology company that provides corporate cards equipped with spend management software.

Magic

Monetizr

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Monetizr – Intelligent Rewards Platform for Gaming

Magic

Go Nimbly

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RevOps leaders. Giving SaaS companies the tools to eliminate operational silos and increase revenue by 26%.

Magic

Asseta

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Asseta is an online marketplace for used capital equipment and parts.

Magic

Yodel.io

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Voice that lives where you work. The smart phone system for customer service teams.

Magic

Scribe

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Scribe lets you convert all your favorite apps into completely customizable Slack Bots, within 5 minutes.

Magic

Modalyst

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SaaS, Automation, Marketplace, Dropshipping Software

Magic

Tumble

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Tumble offers a modern laundry experience to tenants.

Magic

BrightFunnel

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BrightFunnel generates predictive, actionable revenue insights for B2B marketers.

Magic

VCV

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VCV is an AI-powered robot recruiter.

Magic

Sales Hacker

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Sales Hacker is an internet company that specializes in the fields of media entertainment, B2B, events, and SaaS.

Magic

MixRank

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MixRank combines robust Mobile App & Web Intelligence with a LiveScan Contacts Engine to Automate Lead Generation

Magic

WHIP Mobility

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B2B SAAS platform for auto dealerships to transform their CX. Sample the experience possible: https://youtu.be/MwWjEErnn2c

Magic

Fletch

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Fletch provides ready-to-use analytics organized in solutions sets that are easy to understand and actionable on day one.

Magic

Duco Experts

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Duco is an online marketplace that features direct messaging, single point of billing, and project management dashboard.

Magic

CarForce

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CarForce is a multi-brand enterprise software platform that delivers real-time vehicle health insights using EDGE computing and ML

Magic

SmartShoot

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SmartShoot is a technology platform connecting brands with professional photographers and videographers to produce custom photos and videos.

Magic

ShortPoint, Inc.

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ShortPoint is a subscription software that helps to build intranets with no coding from their existing content systems.

Magic

Open Packaging Network

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B2B Data-driven industrial platform, generates Circular Economy Solutions for brands & manufacturers across the globe.

Magic

OpenPhone

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OpenPhone offers a phone app that lets users seamlessly get a business phone number without a second phone or a second SIM card.

Magic

Laserfocus

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Laserfocus helps streamline sales processes to help increase sales productivity.

Magic

Bouxtie

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Bouxtie allows you to instantly send a personalized digital gift cards.

Magic

Hexa

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Hexa entirely automates all of the menial tasks that reps are doing today, through one single operator.

Magic

Response

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The single interface to all your vendors.

Magic

hopps

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An iOS / Android platform that reduces the hassle and time for patrons to get a drink while boosting revenue for venues.

Magic

Full Harvest

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Full Harvest is the first B2B marketplace for ugly and surplus produce.

Magic

AutoHub

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AutoHub is a B2B marketplace for auto dealerships.

Magic

Enable

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Rebate management software

Magic

PayrollHero

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PayrollHero is a startup aimed at streamlining payroll and time and attendance tracking for iOS devices.

Magic

Peerlyst

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Peerlyst is a Social network exclusively for security professionals.

Magic

Hazel

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Hazel’s software gives clarity on where your managers are struggling, and effective growth plans to help develop their skills.

Magic

Everythink

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All things in One. Where Infinity starts.

Magic

RainmakerForce

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Sales CRM with AI for B2B salespeople to light up customers who go dark and to get them ready to purchase

Magic

Get Lighthouse

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Lighthouse is software that makes better managers.

Magic

Sway Finance

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Sway Finance is bringing artificial intelligence to the accounting industry.

Magic

Pixc

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Pixc helps online stores increase their sales with better product images.

Magic

Periscope Data

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Periscope Data is the most powerful, flexible analytics platform for data professionals and business users.

Magic

SpeakUp

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Employee-sourced problem solving and ideation

Magic

OrderCircle

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B2B / wholesale cart – the simplicity of Shopify, but for B2B e-commerce.

Magic

VoiceLayer

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Real-time Push-to-Talk PaaS Add realtime Push-to-Talk (PTT) to any app with our simple API/SDK! Push-to-Talk: Messages are streamed rea

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