Indianapolis Healthcare Innovators: Emerging US-Based Startups Revolutionizing the Industry

January 27, 2024

In this article, we take a look at some of the most innovative health care startups that were established in 2020 or later and are headquartered in Indianapolis, Indiana. These companies range from biomarker-based diagnostics to biotechnology, digital health, and elder care. Their innovative contributions to the health care industry are helping to shape the future of medicine and patient care.

Indianapolis has become a hub for health care startups, attracting top talent and investment. The city’s vibrant tech scene, deep pool of health care professionals, and supportive startup community make it an ideal launching pad for fledgling health care companies. These startups are leveraging the latest technologies to create products and services aimed at improving patient outcomes and transforming the health care industry.

While it’s still early days for these companies, their innovative ideas and approaches suggest that they have a bright future ahead. Here is a closer look at these promising startups.

Early is Good

Founded by HL Ananda Piyankara, and Thakshila Liyanage, Early is Good is known for its biomarker-based approach that enables early, accurate, and accessible detection of renal system diseases. Founded in 2020, the company is based in Indianapolis, Indiana. [LinkedIn]

Grannus Therapeutics

Grannus Therapeutics is a biotechnology company founded by John Foglesong and Sanket Mishra in 2020. The company focuses on the development of small-molecule inhibitors for specific isoforms of HSP90 and is headquartered in Indianapolis, Indiana. [LinkedIn]

Hickory Recovery Network

Hickory Recovery Network is a residential drug rehab treatment and alcohol detox program provider. The company offers residential and outpatient programs for adults suffering from substance use disorders and co-occurring mental health illnesses. [Facebook | LinkedIn]

P1 Dental Partners

P1 Dental Partners is a dental service company based in Indianapolis, Indiana. They focus on providing dental services of the highest quality. [Facebook | LinkedIn]


Based in Indianapolis, Indiana, Compel focuses on offering beauty and personal health care products and services. [Facebook | LinkedIn]


Portum is a mobile health app company based in Indianapolis, Indiana. [Facebook | LinkedIn]

Med 1 Solutions

Based in Indianapolis, Indiana, Med 1 Solutions focuses on offering consulting and payment solutions for the health care industry. [Facebook | LinkedIn]


PurposeCare is an integrated platform company that coordinates community care with a special emphasis on individuals who are dual eligible for Medicaid and Medicare. [LinkedIn]

Health & Hospital Corporation of Marion County (HHC)

The Health & Hospital Corporation of Marion County (HHC) is a consulting agency focused on the hospital industry, headquartered in Indianapolis. [LinkedIn]

Envive Healthcare

Envive Healthcare is an elder care service provider based in Indianapolis, Indiana. [Facebook | LinkedIn]

Indy Developmental Residential Service

Indy Developmental Residential Service provides health care and rehabilitation services in Indianapolis, Indiana. [Facebook | LinkedIn]

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