Revolutionary San Francisco Startups Pushing Boundaries in US Machine Learning

January 26, 2024

The landscape of Silicon Valley startups is filled with success stories, potential unicorns and cutting-edge technological breakthroughs. In 2020, the rise of companies operating in the Machine Learning industry is trending, particularly in San Francisco, California. Their impact across sectors, such as finance, health care, music, retail, and more, is noteworthy. Let’s delve into the top ten rise of these startups founded in 2020 that’s worth keeping an eye on in the Machine Learning industry.

Machine learning has dominated tech innovation for the last few years. Renowned for its ability to automate processes, improve business performance, and transform user experiences, these startups aim to leverage the power of machine learning to reshape their respective industries. San Francisco, known for being a hotbed for innovative startups, didn’t disappoint in 2020 and shows promising signs for 2021.

This article highlights some of these startups that have evolved in San Francisco, California, focusing specifically on their inception, founders, industry and how their business strives to make a difference via machine learning.


Founded in 2020, Butter provides a payment intelligence platform for resolving payment failures. Created by founder Vijay Menon, Butter’s patented technology optimizes each payment for individual success. Its real-time decision automation is powered by machine learning, making its product far more effective than other tools in the fintech industry. Find more details on their Facebook and LinkedIn pages.

Surge AI

Recognized as the world’s most potent data labeling platform, Surge AI, was launched by Edwin Chen in 2020. The company provides lightning-fast data labelers, creating datasets enriched with language intricacies. Surge AI’s mix of advanced technology, quality controls, and robust APIs redefine sophisticated labeling. You can follow Surge AI on their LinkedIn and Facebook pages.


Poised is an AI-powered communication coach that provides personalized feedback and lessons by observing online meetings. The company was founded by Charles Hua, Soumya Mohan, and Vicky Sehrawat. You can learn more about them on their Facebook and LinkedIn pages.


Co-founded by brothers Arnav Sharma and Varun Sharma in 2020, Enterpret aids companies in analyzing customer feedback and assists in product development. The company is based in San Francisco, California, and you can follow them on LinkedIn.


Founded by Paxton Maeder-York in 2020, Alife develops artificial intelligence tools to assist physicians in increasing a patient’s chances of pregnancy success. Alife’s mission is to help people have healthy children by connecting fertility specialists to patients. Further details are available on their Facebook and LinkedIn pages.


Founded by Jessica Powell and Luke Miner, Audioshake has built an on-demand platform and API that allows musicians, audio engineers, producers, and more to unlock their audio content for various uses. Audioshake’s patented technology is used by major labels, music publishers, film production studios, and more.


Co-founded by Cyril Brignone and Gregory Haardt, Vectice powers data and AI initiatives with its cloud-based platform. The company aims to revolutionize enterprise data science teams’ asset tracking, knowledge management, and business collaboration. You can follow them on LinkedIn.


Aquarium Learning is an ML data management platform founded in 2020 by Peter Gao and Quinn Johnson. It helps to improve models by refining datasets. The company is based in San Francisco, California, and you can follow them on LinkedIn.


Maple is a family tech app co-founded by Michael Perry and Mike Taylor in 2020. The app uses AI and machine learning technology to build daily and weekly personalized plans for parents, providing smarter recommendations based on their needs. Find more about them on their Facebook and LinkedIn pages.

nSight Surgical

Founded by Derek Amanatullah, Nathaniel Smith, and Nathaniel Smith, nSight is revolutionizing surgery with the first machine learning platform to ensure hospital patient safety and streamline operative workflow. The platform improves patient safety by recognizing patient safety moments in the operating room and increasing efficiency across the hospital ecosystem. You can follow them on LinkedIn.


Fountain9 offers a predictive inventory planning and optimization solution for CPG and retail. Founded by Niki Khokale and Rajas Lonkar, Fountain9 uses AI to accurately predict future inventory imbalances. Kronoscope, the company’s flagship product, uses demand sensing and a pricing engine to predict future inventory requirements and optimize prices. Find more information about Fountain9 on their Facebook and LinkedIn pages.

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